Biraz profosyonelce olacak bu yayınlar ama genel bir bilgi sahibi olunsa da fena olmaz. Bilgi güçtür. Bu çalışmada karbonhidrattan fakir diyetin akne belirtilerini azalttığı saptanmış. İki gruba ayrılan hasta grubunun ilkinde karbonhidrat kısıtlamasına gidilirken diğer grupta kısıtlama yapılmamış. 4 ayın sonunda karbonhidrat kısıtlaması yapılan grupta akne belirtileri daha çok düzelmiş....ben böyle bir bilgiyi ilk kez okuyorum... A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial.School of Applied Sciences, RMIT University, Melbourne, Australia.
Bu mail adresi spam botlara karşı korumalıdır, görebilmek için Javascript açık olmalıdır
BACKGROUND: Although the pathogenesis of acne is currently unknown, recent epidemiologic studies of non-Westernized populations suggest that dietary factors, including the glycemic load, may be involved. OBJECTIVE: The objective was to determine whether a low-glycemic-load diet improves acne lesion counts in young males. DESIGN: Forty-three male acne patients aged 15-25 y were recruited for a 12-wk, parallel design, dietary intervention incorporating investigator-blinded dermatology assessments. The experimental treatment was a low-glycemic-load diet composed of 25% energy from protein and 45% from low-glycemic-index carbohydrates. In contrast, the control situation emphasized carbohydrate-dense foods without reference to the glycemic index. Acne lesion counts and severity were assessed during monthly visits, and insulin sensitivity (using the homeostasis model assessment) was measured at baseline and 12 wk. RESULTS: At 12 wk, mean (+/-SEM) total lesion counts had decreased more (P=0.03) in the low-glycemic-load group (-23.5 +/- 3.9) than in the control group (-12.0 +/- 3.5). The experimental diet also resulted in a greater reduction in weight (-2.9 +/- 0.8 compared with 0.5 +/- 0.3 kg; P<0.001) and body mass index (in kg/m(2); -0.92 +/- 0.25 compared with 0.01 +/- 0.11; P=0.001) and a greater improvement in insulin sensitivity (-0.22 +/- 0.12 compared with 0.47 +/- 0.31; P=0.026) than did the control diet. CONCLUSION: The improvement in acne and insulin sensitivity after a low-glycemic-load diet suggests that nutrition-related lifestyle factors may play a role in the pathogenesis of acne. However, further studies are needed to isolate the independent effects of weight loss and dietary intervention and to further elucidate the underlying pathophysiologic mechanisms.
Hidradenitis suppurativa and zinc: a new therapeutic approach. A pilot study.Department of Dermatology, INSERM U601, CHU Hôtel-Dieu, Nantes, France. BACKGROUND: Hidradenitis suppurativa (Verneuil's disease) is a chronic suppurative dermatosis involving apocrine glands with a severe impact on the quality of life, which is enhanced by the fact that the drugs usually prescribed are poorly effective. OBJECTIVE: We discuss a new therapeutic approach based on zinc salts. METHODS: We performed a pilot study on 22 patients, mainly from grade I or II in Hurley's classification. All included patients had previously been prescribed a treatment (antibiotic, isotretinoin, surgery or anti-androgens), which was inefficient. They were then treated with 90 mg of zinc gluconate per day (15 mg zinc per Rubozinc capsule). RESULTS: We observed a clinical response in all patients, with 8 complete remissions (CR) and 14 partial remissions (PR). When CR was obtained, the treatment was progressively decreased (average of 3.5 capsules/day); 4/22 patients experienced side-effects, mainly gastro-intestinal. CONCLUSION: Zinc salts could provide a new therapeutic alternative for the treatment of hidradenitis suppurativa. 2007 S. Karger AG, Basel |